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DnaG (DNA primase) is an essential enzyme involved in the DNA replication fork. Organic mechanism of oligonucleotide synthesis of ribonucleic acid (RNA) in the 5' to 3' direction. DnaG catalyzes the synthesis of oligonucleotides in five discrete steps: template binding, nucleoside triphosphate (NTP) binding, initiation, extension to form a ...
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DnaG can bind directly with the DnaB hexamer, and it seems that the presence of multiple DnaG proteins hovering around the advancing replication fork permits the rapid deposition of primase and microinitiation. In order to keep up with leading strand synthesis, deposition of DnaG must occur at a rate of about 1 event per second.
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